{"id":2513,"date":"2018-09-01T17:21:00","date_gmt":"2018-09-01T15:21:00","guid":{"rendered":"https:\/\/centroandaluzalfa1.org\/?p=2513"},"modified":"2020-04-07T20:48:20","modified_gmt":"2020-04-07T18:48:20","slug":"are-there-differences-between-the-available-treatments-for-pulmonary-emphysema-due-to-alpha-1-antitrypsin-deficiency","status":"publish","type":"post","link":"https:\/\/centroandaluzalfa1.org\/en\/are-there-differences-between-the-available-treatments-for-pulmonary-emphysema-due-to-alpha-1-antitrypsin-deficiency\/","title":{"rendered":"Are there differences between the available treatments for pulmonary emphysema due to Alpha-1 antitrypsin deficiency?"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"2513\" class=\"elementor elementor-2513\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-56fd13ce elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"56fd13ce\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-645deb4a\" data-id=\"645deb4a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6a31893 elementor-widget elementor-widget-text-editor\" data-id=\"6a31893\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h6><span style=\"color: #000000;\">An editorial has recently been published in the Archives of Bronchopneumology that analyzes the differences between the approved treatments for the treatment of pulmonary emphysema due to Alpha-1 deficiency.<\/span><\/h6>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6d5c3134 elementor-widget elementor-widget-text-editor\" data-id=\"6d5c3134\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>Esquinas C, Miravitlles M. Arch Bronconeumol. 2018;54:451-452.<\/em><\/p><p><strong>This publication reflects the differences between the approved treatments for pulmonary emphysema due to Alpha-1 atitrypsin deficiency in Spain, Prolastina\u00ae (Grifols Deutchsland GmbH, Germany) and Respreeza\u00ae (CSL Behring GmbH, Germany).<\/strong><\/p><p>The approval of both drugs is based on the demonstrated biochemical efficacy for maintains the plasma and pulmonary interstitial levels of Alpha-1 Antitrypsin, to prevent lung destruction and slow the progression of pulmonary emphysema.<\/p><p>The main differences are found in the diluted volume difference for each 1 gr vial (40 ml for Prolastin<strong>\u00ae<\/strong> and 20 ml for Respreeza<strong>\u00ae<\/strong>), the degree of biochemical purity and specific activity, without any correlation between purity, tolerability and clinical efficacy.<\/p><p>Although both preparations have similar characteristics, since they are blood products, they should not be substituted during treatment (without the prescription of the responsible doctor), because traceability would be lost in the event of adverse effects or the appearance of communicable diseases.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dbf3c57 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dbf3c57\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e4d1b61\" data-id=\"e4d1b61\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-30cb4a1 elementor-widget elementor-widget-button\" data-id=\"30cb4a1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/www.archbronconeumol.org\/es-existen-diferencias-entre-tratamientos-disponibles-articulo-S0300289618300218?referer=buscador\" target=\"_blank\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Read publication<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>An editorial has recently been published in the Archives of Bronchopneumology that analyzes the differences between the approved treatments for the treatment of pulmonary emphysema due to Alpha-1 deficiency. Esquinas C, Miravitlles M. Arch Bronconeumol. 2018;54:451-452. This publication reflects the differences between the approved treatments for pulmonary emphysema due to Alpha-1 atitrypsin deficiency in Spain, [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[64],"tags":[],"class_list":["post-2513","post","type-post","status-publish","format-standard","hentry","category-aatd-up-to-date"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Are there differences between the available treatments for pulmonary emphysema due to Alpha-1 antitrypsin deficiency? - Centro Andaluz Alfa-1<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/centroandaluzalfa1.org\/en\/are-there-differences-between-the-available-treatments-for-pulmonary-emphysema-due-to-alpha-1-antitrypsin-deficiency\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Are there differences between the available treatments for pulmonary emphysema due to Alpha-1 antitrypsin deficiency? - Centro Andaluz Alfa-1\" \/>\n<meta property=\"og:description\" content=\"An editorial has recently been published in the Archives of Bronchopneumology that analyzes the differences between the approved treatments for the treatment of pulmonary emphysema due to Alpha-1 deficiency. 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