{"id":26375,"date":"2026-05-27T20:21:48","date_gmt":"2026-05-27T18:21:48","guid":{"rendered":"https:\/\/centroandaluzalfa1.org\/?p=26375"},"modified":"2026-05-27T20:22:42","modified_gmt":"2026-05-27T18:22:42","slug":"european-alpha-1-antitrypsi-deficiency-day","status":"publish","type":"post","link":"https:\/\/centroandaluzalfa1.org\/en\/european-alpha-1-antitrypsi-deficiency-day\/","title":{"rendered":"European Alpha-1 Antitrypsin Deficiency Day"},"content":{"rendered":"\n<h2 class=\"wp-block-heading has-vivid-purple-color has-text-color has-link-color wp-elements-2e4504028778e6527bee9095c0055aa1\"><strong>European Alpha-1 Antitrypsin Deficiency Day<\/strong><\/h2>\n\n\n\n<p>On April 25, 2026, we celebrated European Alpha-1 Antitrypsin Deficiency (AATD) Awareness Day.<\/p>\n\n\n\n<p>The aim of this Awareness Day is to <strong>raise awareness about this genetic condition<\/strong> in order to increase detection and diagnosis rates, and ultimately, improve access to treatment for those affected.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<div style=\"aspect-ratio:unset;\" class=\"wp-block-cover alignfull has-parallax\"><div class=\"wp-block-cover__image-background wp-image-25916 size-full has-parallax\" style=\"background-position:50% 50%;background-image:url(https:\/\/centroandaluzalfa1.org\/wp-content\/uploads\/2025\/04\/dia-europeo-de-la-deficiencia-de-alfa-1-antitripsina-1.jpg)\"><\/div><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-40 has-background-dim\" style=\"background-color:#000000\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-constrained wp-container-core-column-is-layout-2c355246 wp-block-column-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30);padding-left:var(--wp--preset--spacing--30)\">\n<h2 class=\"wp-block-heading has-ast-global-color-6-color has-text-color has-link-color wp-elements-25ba027d8c8a1a8db064ffbe82a24509\" style=\"margin-top:var(--wp--preset--spacing--30);margin-right:0;margin-bottom:var(--wp--preset--spacing--30);margin-left:0\">KNOW YOUR GENETICS<\/h2>\n\n\n\n<p class=\"has-vivid-purple-color has-ast-global-color-5-background-color has-text-color has-background has-link-color wp-elements-8db1f2236fa6122976d23357f75a99f8\" style=\"margin-top:0;margin-right:10px;margin-bottom:0;margin-left:10px;padding-top:var(--wp--preset--spacing--30);padding-right:10px;padding-bottom:var(--wp--preset--spacing--30);padding-left:10px\"><strong>DISCOVER THE RISKS TO YOUR HEALTH<\/strong><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-ast-global-color-5-color has-text-color has-link-color wp-elements-ea80023d7b06fe60bb675015713ace54\" style=\"margin-top:0;margin-right:var(--wp--preset--spacing--20);margin-bottom:0;margin-left:var(--wp--preset--spacing--20);font-size:18px\">Alpha-1 Antitrypsin Deficiency is a genetic disease that can cause lung, liver, and skin diseases.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<figure class=\"wp-block-pullquote has-vivid-purple-color has-text-color has-link-color wp-elements-983eeb4eeb05fd16dc8beaa581681e29\" style=\"margin-top:0;margin-bottom:0;padding-top:0;padding-bottom:0;font-size:15px\"><blockquote><p>HEALTH PROBLEMS,<br>SOMETIMES YOU CAN&#8217;T SEE OR FEEL THEM<\/p><cite>Alpha-1 Antitrypsin (AAT) is a protein that protects our organs from external agents.<\/cite><\/blockquote><\/figure>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\" style=\"padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\"><figure class=\"wp-block-media-text__media\"><img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"623\" src=\"https:\/\/centroandaluzalfa1.org\/wp-content\/uploads\/2025\/03\/pacientes-alfa-1.png\" alt=\"\" class=\"wp-image-25894 size-full\"\/><\/figure><div class=\"wp-block-media-text__content\">\n<p style=\"margin-right:14px;margin-left:14px\">Hereditary mutations result in an abnormal AAT protein.<\/p>\n\n\n\n<ul style=\"margin-right:0.7rem;margin-left:0.7rem\" class=\"wp-block-list\">\n<li>This protein accumulates in the liver and can cause organ damage.<\/li>\n\n\n\n<li>Consequently, if the level of AAT in the blood is low, the lungs are left unprotected against infections or irritants, and lung problems can develop.<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<p><\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-vivid-purple-color has-alpha-channel-opacity has-vivid-purple-background-color has-background is-style-default\" style=\"margin-top:var(--wp--preset--spacing--60);margin-bottom:var(--wp--preset--spacing--60)\"\/>\n\n\n\n<h4 class=\"wp-block-heading has-text-align-left has-vivid-purple-color has-ast-global-color-5-background-color has-text-color has-background has-link-color wp-elements-534001eff637016c69eebd9d01c5f314\" style=\"margin-top:var(--wp--preset--spacing--20);margin-right:0;margin-bottom:var(--wp--preset--spacing--20);margin-left:0;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">RECOGNIZE THE SIGNS<\/h4>\n\n\n\n<h3 class=\"wp-block-heading has-text-align-left has-ast-global-color-5-color has-vivid-purple-background-color has-text-color has-background has-link-color wp-elements-e8a69ac450be0878a5ebfcdfe5f42d8f\" style=\"margin-top:0;margin-right:0;margin-bottom:0;margin-left:0;padding-top:0;padding-right:10px;padding-bottom:0;padding-left:10px\"><strong>European Alpha-1 Antitrypsin Deficiency Day<\/strong><\/h3>\n\n\n\n<p class=\"has-text-align-left\" style=\"padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20);font-size:15px\">Alpha-1 antitrypsin deficiency (AATD) can cause a variety of symptoms that may begin at a young age or in adulthood (between 20 and 50 years old).<\/p>\n\n\n\n<div class=\"wp-block-media-text has-media-on-the-right is-stacked-on-mobile\"><div class=\"wp-block-media-text__content\">\n<h4 class=\"wp-block-heading has-vivid-purple-color has-text-color has-link-color wp-elements-840b6dd3019cf4ff446ed14e50455aac\">BABIES AND CHILDREN<\/h4>\n\n\n\n<h5 class=\"wp-block-heading has-ast-global-color-5-color has-vivid-purple-background-color has-text-color has-background has-link-color wp-elements-e2386f046da8d047a5bbdcf2fcd72037\" style=\"padding-top:var(--wp--preset--spacing--20);padding-right:10px;padding-bottom:var(--wp--preset--spacing--20);padding-left:10px\">LIVER-RELATED SYMPTOMS<\/h5>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Jaundice (yellowing of the skin and\/or eyes)<\/li>\n\n\n\n<li>Abdominal pain and\/or swelling (infants)<\/li>\n\n\n\n<li>Failure to thrive or lack of normal weight gain (infants)<\/li>\n\n\n\n<li>Diarrhea (infants)<\/li>\n<\/ul>\n<\/div><figure class=\"wp-block-media-text__media\"><img decoding=\"async\" width=\"1024\" height=\"623\" src=\"https:\/\/centroandaluzalfa1.org\/wp-content\/uploads\/2025\/05\/asma-centro-andaluz-alfa-1.png\" alt=\"\" class=\"wp-image-25926 size-full\"\/><\/figure><\/div>\n\n\n\n<p><\/p>\n\n\n\n<h4 class=\"wp-block-heading has-vivid-purple-color has-text-color has-link-color wp-elements-0a3efc7ffd20ddbe3c7c246ec8395395\" style=\"margin-top:var(--wp--preset--spacing--20);margin-right:0px;margin-bottom:var(--wp--preset--spacing--20);margin-left:0px;padding-right:0;padding-left:0;font-size:20px\"><a href=\"ADULTS: RELATED SYMPTOMS\">ADULTOS: S\u00cdNTOMAS RELACIONADOS<\/a><\/h4>\n\n\n\n<p><strong>LUNGS<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Difficulty breathing<\/li>\n\n\n\n<li>Wheezing<\/li>\n\n\n\n<li>Chronic bronchitis<\/li>\n\n\n\n<li>Recurrent colds<\/li>\n\n\n\n<li>Bronchiectasis<\/li>\n<\/ul>\n\n\n\n<p><strong>LIVER<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Jaundice: yellowing of the skin and\/or eyes.<\/li>\n\n\n\n<li>Pain and\/or swelling in the abdomen and\/or legs.<\/li>\n\n\n\n<li>Persistent itching. Feelings of weakness and fatigue.<\/li>\n<\/ul>\n\n\n\n<p><strong>SKIN<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>N\u00f3dulos rojos, dolorosos y elevados en la piel en piernas, brazos, tronco o cara.<\/li>\n\n\n\n<li>Los n\u00f3dulos pueden ulcerarse, sangrar y supurar una sustancia aceitosa.<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h4 class=\"wp-block-heading has-text-align-left has-vivid-purple-color has-ast-global-color-5-background-color has-text-color has-background has-link-color wp-elements-101df22dd1dcf5cec0449de7a08a502e\" style=\"padding-top:0;padding-right:0;padding-bottom:0;padding-left:0;font-size:18px\">Red, painful, raised nodules on the skin of the legs, arms, torso, or face.<\/h4>\n\n\n\n<p class=\"has-text-align-left\">The nodules may ulcerate, bleed, and ooze an oily substance.<\/p>\n\n\n\n<h3 class=\"wp-block-heading has-text-align-left has-ast-global-color-5-color has-vivid-purple-background-color has-text-color has-background has-link-color wp-elements-f962bfb55ea604e5ddda3e7edaadcdc4\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--30);padding-right:10px;padding-bottom:var(--wp--preset--spacing--30);padding-left:10px\"><strong>European Alpha-1 Antitrypsin Deficiency Day<\/strong><\/h3>\n\n\n\n<ol style=\"margin-top:var(--wp--preset--spacing--30);margin-bottom:var(--wp--preset--spacing--30)\" class=\"wp-block-list\">\n<li>It is important that all people with alpha-1 antitrypsin deficiency undergo t<strong>esting for liver disease<\/strong>.<\/li>\n\n\n\n<li>After alpha-1 antitrypsin deficiency (AATD), it is important to be <strong>tested for lung disease<\/strong> as soon as possible.<\/li>\n\n\n\n<li>A <strong>healthy lifestyle<\/strong>, treatment, and symptom management can help prevent lung disease from worsening.<\/li>\n\n\n\n<li>Panniculitis is a rare <strong>skin condition<\/strong>; treatment can help manage it.<\/li>\n<\/ol>\n\n\n\n<figure class=\"wp-block-pullquote has-vivid-purple-color has-text-color has-link-color wp-elements-3039edb4661a5e93e9dc3b78f1249b32\" style=\"margin-top:0;margin-right:0;margin-bottom:0;margin-left:0;padding-top:0;padding-bottom:0;font-size:15px\"><blockquote><p>THE HIDDEN LINK BEHIND UNEXPLAINED SYMPTOMS<\/p><cite>9 out of 10 people with AATD don&#8217;t know they have it:<br><strong>The key is diagnosis.<\/strong><\/cite><\/blockquote><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p class=\"has-text-align-left\">Many people are unaware that they may be living with an undiagnosed inherited condition.<\/p>\n\n\n\n<p class=\"has-vivid-purple-color has-text-color has-link-color wp-elements-a401033bee9b17f770762e3c8ae62cb2\"><strong>Diagnosis is key to:<\/strong><\/p>\n\n\n\n<ul style=\"padding-top:0;padding-bottom:0\" class=\"wp-block-list\">\n<li style=\"margin-top:0;margin-bottom:0\">Access to <strong>treatments<\/strong>.<\/li>\n\n\n\n<li>Following<strong> care plans <\/strong>and lifestyle changes.<\/li>\n\n\n\n<li>Ultimately, <strong>slowing the progression of the disease<\/strong> and improving quality of life.<\/li>\n\n\n\n<li>It can also give your children <strong>the knowledge <\/strong>they need to act in time.<\/li>\n\n\n\n<li>And with that, potentially <strong>preventing symptoms<\/strong> before they appear.<\/li>\n<\/ul>\n\n\n\n<p><\/p>\n\n\n\n<div class=\"wp-block-cover alignfull has-parallax\" style=\"margin-top:0;margin-bottom:0;padding-top:0;padding-bottom:0;aspect-ratio:unset;\"><div class=\"wp-block-cover__image-background wp-image-25916 size-full has-parallax\" style=\"background-position:50% 50%;background-image:url(https:\/\/centroandaluzalfa1.org\/wp-content\/uploads\/2025\/04\/dia-europeo-de-la-deficiencia-de-alfa-1-antitripsina-1.jpg)\"><\/div><span aria-hidden=\"true\" class=\"wp-block-cover__background has-background-dim-40 has-background-dim\" style=\"background-color:#000000\"><\/span><div class=\"wp-block-cover__inner-container is-layout-flow wp-block-cover-is-layout-flow\">\n<div class=\"wp-block-columns alignwide is-layout-flex wp-container-core-columns-is-layout-28f84493 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-constrained wp-container-core-column-is-layout-2c355246 wp-block-column-is-layout-constrained\" style=\"padding-right:var(--wp--preset--spacing--30);padding-left:var(--wp--preset--spacing--30)\">\n<h2 class=\"wp-block-heading has-ast-global-color-6-color has-text-color has-link-color wp-elements-ac8ffc93868694379a9f223bce4e8c70\" style=\"margin-top:0;margin-right:0;margin-bottom:0;margin-left:0\">DISCOVER IF IT&#8217;S PART OF YOUR STORY<\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-ast-global-color-5-color has-text-color has-link-color wp-elements-7624fd68952c24116c10cb66da6c6e8c\" style=\"margin-top:0;margin-right:var(--wp--preset--spacing--70);margin-bottom:0;margin-left:var(--wp--preset--spacing--70);font-size:18px\">Don&#8217;t miss the opportunity to find out if something makes you vulnerable; all it takes is a <strong>blood test<\/strong> to measure your AAT levels.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p><\/p>\n\n\n\n<p>If your <strong>AAT levels are low<\/strong>, a genetic test can confirm the diagnosis by identifying the specific genetic variants involved and determining the severity of the deficiency. Understanding your genetic makeup is the first step in protecting your health.<\/p>\n\n\n\n<p class=\"has-vivid-purple-color has-text-color has-link-color wp-elements-39af5da1feecd86db02ed62235e34173\"><strong>We remind you of the importance of getting tested.<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>In particular, all patients with liver disease of unknown origin and those who suffer from frequent respiratory infections should be tested.<\/li>\n\n\n\n<li>Likewise, people with a family history of alpha-1 antitrypsin deficiency, those with COPD, bronchiectasis, or irreversible asthma should also be screened.<\/li>\n<\/ul>\n\n\n\n<p class=\"has-vivid-purple-color has-text-color has-link-color wp-elements-dbf5eb9b9f3cc0ee6a1ce77ebb0ef481\">Don&#8217;t wait until your symptoms get worse! Get tested now!<\/p>\n\n\n\n<div class=\"wp-block-media-text has-media-on-the-right is-stacked-on-mobile\" style=\"margin-right:0;margin-left:0\"><div class=\"wp-block-media-text__content\">\n<h5 class=\"wp-block-heading has-ast-global-color-5-color has-vivid-purple-background-color has-text-color has-background has-link-color wp-elements-77157b5684fb4bd73a608eaa5d959a2d\" style=\"margin-top:0;margin-right:0px;margin-bottom:0;margin-left:0px;padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20)\">NEXT STEP<\/h5>\n\n\n\n<p style=\"margin-top:var(--wp--preset--spacing--30);margin-right:0;margin-bottom:var(--wp--preset--spacing--30);margin-left:0\">After the diagnosis, you should contact a specialized center of excellence or a specialist doctor.<\/p>\n<\/div><figure class=\"wp-block-media-text__media\"><img decoding=\"async\" width=\"600\" height=\"300\" src=\"https:\/\/centroandaluzalfa1.org\/wp-content\/uploads\/2021\/09\/ASISTENCIA-PACIENTES-DAAT.png\" alt=\"\" class=\"wp-image-5542 size-full\" srcset=\"https:\/\/centroandaluzalfa1.org\/wp-content\/uploads\/2021\/09\/ASISTENCIA-PACIENTES-DAAT.png 600w, https:\/\/centroandaluzalfa1.org\/wp-content\/uploads\/2021\/09\/ASISTENCIA-PACIENTES-DAAT-300x150.png 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/figure><\/div>\n\n\n\n<p><\/p>\n\n\n\n<h4 class=\"wp-block-heading has-text-align-left has-vivid-purple-color has-ast-global-color-5-background-color has-text-color has-background has-link-color wp-elements-84e79c2326fe55f64e35dd98e8f50b72\" style=\"padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">JOIN US TO MAKE A DIFFERENCE<\/h4>\n\n\n\n<p class=\"has-text-align-left\" style=\"padding-right:0;padding-left:0\">Every year on April 25, the Alpha-1 community across Europe comes together to raise awareness, give a voice to patients through their own stories, and highlight the challenges faced by people with alpha-1 antitrypsin deficiency (AATD) and their families.<\/p>\n\n\n\n<p class=\"has-text-align-left has-ast-global-color-3-color has-text-color has-link-color wp-elements-d0b9f77085f2839da9e62d8bea8af4e8\" style=\"padding-right:0;padding-left:0\"><strong>Together, we can build a future where no one with AATD is left behind.<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-left\">There are many treatments and therapies you may be entitled to that can improve your quality of life.<\/p>\n\n\n\n<p class=\"has-text-align-left has-vivid-purple-color has-text-color has-link-color wp-elements-d7284f8dc3689c6daf534aabd0f8d927\">Contact your national patient organization: <a href=\"https:\/\/alfa1.org.es\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Alpha 1 Spain<\/strong><\/a><\/p>\n\n\n\n<figure class=\"wp-block-gallery has-nested-images columns-default is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\"><\/figure>\n\n\n\n<p>Source:<a href=\"https:\/\/alfa1.org.es\/inscripcion-abierta-para-el-8o-foro-de-pacientes-de-separ\/\"> <\/a><a href=\"https:\/\/www.redaat.es\/\">REDAAT<\/a><\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/centroandaluzalfa1.org\/en\/news-on-alpha-1-antitrypsine-deficiency\/\" target=\"_blank\" rel=\"noreferrer noopener\">Read more news<\/a><\/div>\n<\/div>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>On April 25, 2026, we celebrated European Alpha-1 Antitrypsin Deficiency (AATD) Awareness Day.<\/p>\n","protected":false},"author":5,"featured_media":8642,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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