{"id":4377,"date":"2020-11-08T13:37:07","date_gmt":"2020-11-08T12:37:07","guid":{"rendered":"https:\/\/centroandaluzalfa1.org\/?p=4377"},"modified":"2021-01-20T19:22:50","modified_gmt":"2021-01-20T18:22:50","slug":"science-day-genetic-treatments","status":"publish","type":"post","link":"https:\/\/centroandaluzalfa1.org\/en\/science-day-genetic-treatments\/","title":{"rendered":"Science Day: Genetic Treatments"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"4377\" class=\"elementor elementor-4377\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b9a2f23 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b9a2f23\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9d152b0\" data-id=\"9d152b0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9fc811e elementor-widget elementor-widget-heading\" data-id=\"9fc811e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Research on Genetic Diseases<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-abc85b4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"abc85b4\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-ed1697d\" data-id=\"ed1697d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f65c557 elementor-widget elementor-widget-text-editor\" data-id=\"f65c557\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h5 style=\"background-color: #ffffff;\"><span style=\"color: #999999;\">Today, November 10, 2020, we celebrate Science Day.<\/span><\/h5><h5 style=\"background-color: #ffffff;\"><span style=\"color: #999999;\">We want to make special mention of the evolution in genetic treatments.<\/span><\/h5>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-82dabd8\" data-id=\"82dabd8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3246e68 elementor-widget elementor-widget-image\" data-id=\"3246e68\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"626\" height=\"416\" src=\"https:\/\/centroandaluzalfa1.org\/wp-content\/uploads\/2020\/09\/web-subservicios.png\" class=\"attachment-large size-large wp-image-4236\" alt=\"\" srcset=\"https:\/\/centroandaluzalfa1.org\/wp-content\/uploads\/2020\/09\/web-subservicios.png 626w, https:\/\/centroandaluzalfa1.org\/wp-content\/uploads\/2020\/09\/web-subservicios-300x199.png 300w\" sizes=\"(max-width: 626px) 100vw, 626px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b1923a1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b1923a1\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fd14d79\" data-id=\"fd14d79\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3158cd1 elementor-widget elementor-widget-heading\" data-id=\"3158cd1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><h3 data-elementor-setting-key=\"title\" data-pen-placeholder=\"Teclea aqu\u00ed...\" style=\"font-weight: var( --e-global-typography-primary-font-weight );font-family: var( --e-global-typography-primary-font-family ), Sans-serif\"><span style=\"font-family: var( --e-global-typography-primary-font-family ), Sans-serif;font-weight: var( --e-global-typography-primary-font-weight )\"> Evolution in science<\/span><\/h3><\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9df2538 elementor-widget elementor-widget-text-editor\" data-id=\"9df2538\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: bold; color: var( --e-global-color-text );\">Genetic therapy uses genetic material to treat diseases of this group, which, as we already know, Alpha 1 Antitrypsin Deficiency is part of it.<\/span><\/p><p style=\"background-color: #ffffff;\"><span style=\"color: var( --e-global-color-text ); font-weight: var( --e-global-typography-text-font-weight );\">This therapy tries to modulate cell function, being able to correct the deficiency caused by the loss or alteration of a gene, by modifying the expression of proteins.<\/span><\/p><p style=\"background-color: #ffffff;\"><span style=\"color: var( --e-global-color-text ); font-weight: var( --e-global-typography-text-font-weight );\">Thus, protein coding sequences, antisense probes, triple DNA and ribozomes can be considered the drugs of this treatment.<\/span><\/p><p style=\"background-color: #ffffff;\"><span style=\"color: var( --e-global-color-text ); font-weight: var( --e-global-typography-text-font-weight );\"><i>The complexity of this resides in the set of techniques for the distribution of these \u201cdrugs\u201d, that is, the transfer of this material to the target cells.<\/i><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3605774 elementor-widget elementor-widget-heading\" data-id=\"3605774\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Genetic alterations beneficial to health<br><\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f1c6d4c elementor-widget elementor-widget-text-editor\" data-id=\"f1c6d4c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: bold; color: var( --e-global-color-text );\">Thanks to the advance in the knowledge about genetics, mechanisms that regulate cell division and differentiation have been discovered.<\/span><\/p><p style=\"background-color: #ffffff;\">The development of technology has helped to understand the recombination of DNA to amplify the biological response.<\/p><p style=\"background-color: #ffffff;\"><span style=\"color: #00635b;\"><span style=\"font-weight: bold;\">How?<\/span><\/span><\/p><p style=\"background-color: #ffffff;\">Through the identification, isolation and sequencing of functional genes.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-89a314a elementor-widget elementor-widget-heading\" data-id=\"89a314a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\"><i>Gene therapy<\/i><\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b291020 elementor-widget elementor-widget-text-editor\" data-id=\"b291020\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"background-color: #ffffff;\"><span style=\"font-weight: bold;\">The reason for the healthier outlook for gene therapy in 2020 is &#8220;improvements in gene transfer technology.&#8221;<\/span><\/p><p style=\"background-color: #ffffff;\"><span style=\"color: var( --e-global-color-text );\">In the case that concerns us, with respect to respiratory patients with Alpha 1 deficiency, trials have shown some unusual tolerogenic properties.<\/span><\/p><p style=\"background-color: #ffffff;\"><span style=\"color: var( --e-global-color-text );\">The study shows that patients develop regulatory T cells against AAV coat proteins that prevent them from reacting negatively, even without pharmaceutical immunosuppression. &#8220;<\/span><\/p><p style=\"background-color: #ffffff;\"><span style=\"color: var( --e-global-color-text );\">We want to continue celebrating Science Day, thanking all professionals.<\/span><\/p><p style=\"background-color: #ffffff;\"><span style=\"color: #00635b;\"><span style=\"font-weight: bold;\">Especially to health workers and researchers, who ensure the progress and improvement of the quality of life of our patients.<\/span><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c20671f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c20671f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-87759e2\" data-id=\"87759e2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f69c036 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"f69c036\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/centroandaluzalfa1.org\/en\/media\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Read more news<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Research on Genetic Diseases Today, November 10, 2020, we celebrate Science Day. We want to make special mention of the evolution in genetic treatments. Evolution in science Genetic therapy uses genetic material to treat diseases of this group, which, as we already know, Alpha 1 Antitrypsin Deficiency is part of it. This therapy tries to [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":2900,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[62],"tags":[],"class_list":["post-4377","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-others"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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